Barangay San Roque is one of the nine barangays enclosed in the Metro District Division of Barangays in Tarlac City. It bounded by Barangay San Vicente on the West, Barangay Ligtasan on the East, Barangay San Sebastian on the South, and Barangay Cut-Cut 1st on the North.

It is approximately 1.0 kilometer away from city proper. It has a total land area of 96.51 hectares. Mostly the whole parts of this area designated to business establishments and residential area. It is divided also to nine blocks namely Block 1, Block 2, and Block 3 to Block 9.

Barangay San Roque classified as Urban Barangay, it has a total population of seven thousand forty five (7,045) as of 2005, and a household population of one thousand four hundred seventy eight (1,478).

Barangay San Roque is a commercial, industrial and residential area. Different types of business firms like siesta travel brakes, junkshop, lumber store, sash factory, tailoring and many more are situated here. Residents of this barangay were mostly professionals, employees, laborer, construction workers, drivers and others.

Barangay San Roque serves as the Southern porter to the political, religious and economic hub or center of the City and Government of Tarlac. It is one of Tarlac City’s biggest barangays with a population of 7,487 as of May 1, 2000 Statistics. An account of 1849 City that Tarlac grew into 13 Barrio’s, though there was not yet the San Roque toponym also it became part of the history where the Guardia Civil executed Col. Francisco Tañedo in January 1898 during the Spanish regime. The same year, San Roque was already mentioned in documents as one of the center of operations of General Francisco Macabulos against Spaniards.

Barrio San Roque named after San Roque or Saint Rock who is the Powerful Patron of the Sick and the suffering. During the 30th century, it said that many people who were afflicted with dreaded diseases healed through his intercession.

It was March 07, 1969 when a kind couple gave hope for the rise of San Roque parish. It was through the generosity of the Dr. Ernesto G. Cruz and Mrs. Ursula Magat that the 692 Square meter lot intended for the site of a Chapel for the Roman Catholic Church of Barrio San Roque.

Apostolic Mission then came about by the men and women cursillistas of the DECOLORES time. In May 1969, the Holy Rock team was organized. Mr. Ismael C. Dizon Spearheaded it and the charter president was the late Mr. Saturnino Torregoza. Same year thereafter, the promoters of the Lady of Fatima came into reality, as Mrs. Liling Torregoza became the President.

Ninety percent of the total populations are Pampango, and the rest are Tagalog, Bisaya, Pangasinense, and Ilocano.

Barangay San Roque celebrates their Feast Day every August 16 as a thanks giving to their Patron Saint Roch (San Roque). Saint Roch (Latin: Rochus; Catalan: Roc; Italian: Rocco; French: Roch; Spanish and Portuguese: Roque; German: Rochus; c. 1295 – traditionally 16 August 1327[1]) was a Christian saint, a confessor whose death is commemorated on 16 August; he is specially invoked against the plague.